IMPDH1 Polyclonal Antibody Store at -20°C
SKU: E-AB-13333-200
IMPDH1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13333 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human IMPDH1 |
| Abbre | IMPDH1 |
| Synonyms | IMDH1, IMP (inosine monophosphate) dehydrogenase 1, IMP dehydrogenase 1, IMPD, IMPD 1, IMPD1, IMPDH 1, IMPDH I, IMPDH-I, Impdh1, Inosine 5' monophosphate dehydrogenase 1, Inosine monophosphate dehydrogenase 1, Inosine-5''-monophosphate dehydrogenase 1, LCA11, RP10, sWSS |
| Swissprot | |
| Calculated MW | 55 kDa |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular region, Lysosome, azurophil granule lumen, Nucleus, Other locations: cytoplasm, ficolin-1-rich granule lumen, secretory granule lumen. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.