IL1 beta Polyclonal Antibody
Couldn't load pickup availability
Still have questions? Ask our experts!
IL1 beta Polyclonal Antibody
| SKU # | E-AB-40530 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Zebrafish |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant Zebrafish IL 1β protein expressed by E.coli |
| Abbre | IL1 beta |
| Synonyms | IL-1, IL1 beta, IL1-BETA, IL1B, IL1F2 |
| Swissprot | |
| Calculated MW | 30 kDa |
| Observed MW | 30 kDa, 20kDa, 18kDa |
| Cellular Localization | Cytoplasm, cytosol, Lysosome, Secreted, exosome, Cytoplasmic vesicle, autophagosome, Secreted. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-2000 |
Background
There are two genes for interleukin-1: IL-1 alpha and IL-1 beta. IL-1β precursor is cleaved by cytosolic caspase-1 (interleukin-1 beta convertase) to form mature IL-1β. The multiple biologic activities that define IL-1 are properties of a 15- to 18-kDa protein that plays a central role in the regulation of immune and inflammatory responses. Mature IL-1β is a potent pro-inflammatory cytokine involved in fever induction, activation of lymphocytes, and the expression of adhesion molecules on endothelial cells. Dysregulated IL-1β expression is associated with a variety of pathological conditions, including autoimmune diseases, chronic inflammation, and cancer.