IFT74 Polyclonal Antibody Store at -20°C Host Rabbit
SKU: E-AB-16349-200
IFT74 Polyclonal Antibody Store at -20°C Host Rabbit
| SKU # | E-AB-16349 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human IFT74 |
| Abbre | IFT74 |
| Synonyms | CMG 1, CMG-1, Capillary morphogenesis gene 1 protein, Capillary morphogenesis protein 1, Ccdc2, Chlamydomonas, Coiled-coil domain containing 2, Coiled-coil domain-containing protein 2, IFT74, homolog of, intraflagellar transport 74 |
| Swissprot | |
| Cellular Localization | Cytoplasmic vesicle. Intracellular vesicular compartment. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.