HSP105 Polyclonal Antibody
SKU: E-AB-10380-200
HSP105 Polyclonal Antibody
| SKU # | E-AB-10380 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HSPH1 |
| Abbre | HSPH1 |
| Synonyms | Antigen NY CO 25, Antigen NY-CO-25, DKFZp686M05240, He, Heat shock 105kD, Heat shock 105kD alpha, Heat shock 105kD beta, Heat shock 105kDa protein, Heat shock 105kDa protein 1, Heat shock 105kDa/110kDa protein 1, Heat shock 110 kDa protein, Heat shock 110kDa protein |
| Swissprot | |
| Calculated MW | 97 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene.Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.Inhibits HSPA8/HSC70 ATPase and chaperone activities.Highly expressed in testis.Present at lower levels in most brain regions, except cerebellum.Overexpressed in cancer cells.Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.