HNRNPH2 Polyclonal Antibody Reactivity Human
SKU: E-AB-52276-200
HNRNPH2 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52276 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human HNRNPH2 |
| Abbre | HNRNPH2 |
| Synonyms | FTP 3, FTP-3, FTP3, HNRH2, HNRNPH2, HNRPH', HNRPH2, Heterogeneous nuclear ribonucleoprotein H'', Heterogeneous nuclear ribonucleoprotein H2, heterogeneous nuclear ribonucleoprotein H2 (H'), hnRNP H'', hnRNP H2, hnRNPH' |
| Swissprot | |
| Calculated MW | 49 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus>nucleoplasm. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA).These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport.While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm.The hnRNP proteins have distinct nucleic acid binding properties.The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs.It is very similar to the family member HNRPH1.This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype.Alternative splicing results in multiple transcript variants encoding the same protein.Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.