HMGCL Polyclonal Antibody Store at -20°C
SKU: E-AB-15095-200
HMGCL Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15095 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HMGCL |
| Abbre | HMGCL |
| Synonyms | 3 hydroxy 3 methylglutaryl CoA lyase, 3 hydroxy 3 methylglutaryl Coenzyme A lyase, 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase, 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase (hydroxymethylglutaricaciduria), 3-hydroxy-3-methylglutarate-CoA lyase, H, HL |
| Swissprot | |
| Calculated MW | 34 kDa |
| Cellular Localization | Mitochondrion matrix. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene belongs to the HMG-CoA lyase family.It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation.Mutations in this gene are associated with HMG-CoA lyase deficiency.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.