HIPK2 Polyclonal Antibody
SKU: E-AB-19750-200
HIPK2 Polyclonal Antibody
| SKU # | E-AB-19750 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human HIPK2 |
| Abbre | HIPK2 |
| Synonyms | HIPK 2, HIPK2, Hipk2, Homeodomain interacting protein kinase 2, Homeodomain-interacting protein kinase 2, Nbak1, Nuclear body-associated kinase 1, PRO0593, Sialophorin tail-associated nuclear serine/threonine-protein kinase , Stank, hHIPk 2, hHIPk2 |
| Swissprot | |
| Calculated MW | 131 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus>PML body. Cytoplasm. Concentrated in PML/POD/ND10 nuclear bodies. Small amounts are cytoplasmic. |
| Concentration | 1.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene.