GRIK3 Polyclonal Antibody
SKU: E-AB-19967-200
GRIK3 Polyclonal Antibody
| SKU # | E-AB-19967 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GRIK3 |
| Abbre | GRIK3 |
| Synonyms | EAA5, Excitatory amino acid receptor 5, GLR 7, GLR7, GLU R7, GLUR 7, GRIK 3, GRIK3, GluR 7a, GluR-7, GluR7, GluR7a, Glutamate receptor, Glutamate receptor 7, Glutamate receptor ionotropic kainate 3, ionotropic kainate 3 |
| Swissprot | |
| Calculated MW | 104 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cell membrane. Cell junction>synapse>postsynaptic cell membrane. |
| Concentration | 1.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.