GNAT1 Polyclonal Antibody
SKU: E-AB-19919-200
GNAT1 Polyclonal Antibody
| SKU # | E-AB-19919 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GNAT1 |
| Abbre | GNAT1 |
| Synonyms | CSNBAD3, GBT1, GNAT1, GNATR, Guanine nucleotide-binding protein G(t) subunit alpha-1, Rod specific transducin, guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1, guanine nucleotide binding protein G(T) alpha 1 subunit |
| Swissprot | |
| Calculated MW | 40 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytosol, Plasma Membrane, apical plasma membrane, heterotrimeric G-protein complex, photoreceptor disc membrane, photoreceptor outer segment membrane, plasma membrane, Other locations: membrane, neuronal cell body, photoreceptor connecting cilium, photoreceptor inner segment, photoreceptor outer segment. |
| Concentration | 0.66 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.GNAT1 (G Protein Subunit Alpha Transducin 1) is a Protein Coding gene. Diseases associated with GNAT1 include Night Blindness, Congenital Stationary, Autosomal Dominant 3 and Night Blindness, Congenital Stationary, Type 1G. Among its related pathways are Phospholipase-C Pathway and Phototransduction. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GNAT2.