GLUT-3 Polyclonal Antibody Reactivity Human
SKU: E-AB-31557-200
GLUT-3 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-31557 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Glut3 |
| Abbre | GLUT-3 |
| Synonyms | FLJ90380, GLUT 3, GLUT-3, GLUT3, GTR3, Glucose transporter type 3, Glucose transporter type 3 brain, Slc2a3, Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3, Solute carrier family 2, brain, facilitated glucose transporter member 3 |
| Swissprot | |
| Calculated MW | 54 kDa |
| Observed MW | 55 kDa |
| Cellular Localization | Membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
Glucose transporter 3(or GLUT3), also known assolute carrier family 2, facilitated glucose transporter member 3(SLC2A3) is aproteinthat in humans is encoded by theSLC2A3gene. GLUT3facilitatesthe transport ofglucoseacross theplasma membranesof mammalian cells. GLUT3 is most known for its specific expression inneuronsand has originally been designated as the neuronal GLUT. GLUT3 has been studied in other cell types with specific glucose requirements, includingsperm, preimplantationembryos, circulatingwhite blood cellsandcarcinomacell lines. GLUT3 has both a higher affinity for glucose and at least a fivefold greater transport capacity than GLUT1, GLUT2 and GLUT4, which is particularly significant for its role in neuronal glucose transport, where ambient glucose levels are fivefold lower than in serum.