Gamma Tubulin Monoclonal Antibody
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Gamma Tubulin Monoclonal Antibody
| SKU # | E-AB-22137 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide of Gamma Tubulin |
| Abbre | Gamma Tubulin Mouse (6C12) |
| Synonyms | GCP-1, Gamma-1-tubulin, Gamma-tubulin complex component 1, TBG1, TUBG, TUBG1, TUBGCP1, Tubulin, Tubulin gamma-1 chain, gamma 1, gamma polypeptide |
| Swissprot | |
| Observed MW | 50 kDa |
| Cellular Localization | Cytoplasm>cytoskeleton>centrosome. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Signal Transduction |
| Clone No. | 3E4 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-2000 |
| IHC | 1:100-200 |
Background
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. TUBG1 (Tubulin Gamma 1) is a Protein Coding gene. Diseases associated with TUBG1 include Cortical Dysplasia, Complex, With Other Brain Malformations 4 and Reducing Body Myopathy. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and structural constituent of cytoskeleton. An important paralog of this gene is TUBG2.