FHL3 Polyclonal Antibody Store at -20°C
SKU: E-AB-11238-200
FHL3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11238 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human FHL3 |
| Abbre | FHL3 |
| Synonyms | FHL 3, FHL-3, FHL3, Fhl3, Four and a half LIM domains 3, Four and a half LIM domains protein 3, SLIM-2, SLIM2, Skeletal muscle LIM protein 2, Skeletal muscle LIM-protein 2 |
| Swissprot | |
| Calculated MW | 31 kDa |
| Cellular Localization | Cytoskeleton, stress fiber, Nucleus, Other locations: focal adhesion, Z disc. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.