FECH Polyclonal Antibody
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FECH Polyclonal Antibody
FECH Polyclonal Antibody is a rabbit IgG raised against a synthetic peptide of human FECH, also called ferrochelatase. It reacts with human and mouse samples. Recommended dilutions are WB 1:500-1:2000 and IHC 1:50-1:300. The antibody is antigen affinity purified and supplied at 1.56 mg/mL. Its calculated MW is 48 kDa, and the target sits in the mitochondrion inner membrane. SKU E-AB-19863, in 20μL, 60μL, 120μL and 200μL sizes.
| SKU # | E-AB-19863 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FECH |
| Abbre | FECH |
| Synonyms | EPP, FCE, Fch, Fcl, Ferrochelatase, Ferrochelatase (protoporphyria), Ferrochelatase mitochondrial, HEMH, Heme synthase, Heme synthetase, Protoheme ferro lyase, Protoheme ferro-lyase, Protoporphyria, fech, mitochondrial |
| Swissprot | |
| Calculated MW | 48 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Mitochondrion inner membrane. |
| Concentration | 1.56 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cardiovascular, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.