FDFT1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52940-200
FDFT1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52940 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human FDFT1 |
| Abbre | FDFT1 |
| Synonyms | DGPT, ERG9, FDFT, FDFT1, FPP:FPP farnesyltransferase, Farnesyl diphosphate farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, SQS, SS, Squalene synthase, Squalene synthetase |
| Swissprot | |
| Calculated MW | 48 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Endoplasmic reticulum membrane. |
| Concentration | 1.32 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:40-1:200 |
Background
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.