ELAVL1 Polyclonal Antibody Store at -20°C
SKU: E-AB-10301-200
ELAVL1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10301 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ELAVL1 |
| Abbre | ELAVL1 |
| Synonyms | Drosophila) like 1 (Hu antigen R), ELAV (embryonic lethal, ELAV (embryonic lethal abnormal vision Drosophila) like 1, ELAV like 1, ELAV like RNA binding protein 1, ELAV-like protein 1, ELAV1, Elavl1, Embryonic lethal abnormal vision drosophi, abnormal vision |
| Swissprot | |
| Calculated MW | 36 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.