EIF4A1 Monoclonal Antibody
SKU: E-AB-22076-200
EIF4A1 Monoclonal Antibody
| SKU # | E-AB-22076 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Applications | WB, IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | eIF4A1 |
| Synonyms | ATP-dependent RNA helicase eIF4A-1, DDX2, DDX2A, EIF4A, EIF4A1, Eukaryotic initiation factor 4A-I, Eukaryotic initiation factor 4AI, Eukaryotic translation initiation factor , eIF 4A I, eIF-4A-I, eIF4A I, eIF4A-I, eukaryotic translation initiation factor 4A, isoform 1 |
| Swissprot | |
| Observed MW | 48 kDa |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, extracellular matrix, Other locations: cytoplasm, eukaryotic translation initiation factor 4F complex, membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Clone No. | 2B6 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:3000 |
| IHC | 1:50-1:300 |
| IF | 1:100-1:200 |
Background
EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.