DSG1 Polyclonal Antibody Store at -20°C
SKU: E-AB-16389-200
DSG1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-16389 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human DSG1 |
| Abbre | DSG1 |
| Synonyms | CDHF4, Cadherin family member 4, DG1, DGI, DSG, DSG1, Desmoglein-1, Desmosomal glycoprotein 1, EPKHE, EPKHIA, PPKS1, Pemphigus foliaceus antigen, SPPK1 |
| Swissprot | |
| Calculated MW | 114 kDa |
| Cellular Localization | Cell membrane. Cell junction>desmosome. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
Background
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.