CYLD Polyclonal Antibody
SKU: E-AB-16369-200
CYLD Polyclonal Antibody
| SKU # | E-AB-16369 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CYLD |
| Abbre | CYLD |
| Synonyms | BRSS, CDMT, CYLD, CYLD gene, CYLD1, CYLDI, Cyld, Deubiquitinating enzyme CYLD, EAC, HSPC057, KIAA0849, MFT, MFT1, Probable ubiquitin carboxyl terminal hydrolase CYLD, SBS, TEM, Ubiquitin carb, cylindromatosis (turban tumor syndrome), cylindromatosis 1, turban tumor syndrome |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cytoplasm>perinuclear region. Cytoplasm>cytoskeleton. Cell membrane. Detected at the microtubule cytoskeleton during interphase. Detected at the midbody during telophase. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology, Epigenetics and Nuclear Signaling, Tags and Cell markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack. upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme.Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome.Alternate transcriptional splice variants, encoding different isoforms, have been characterized.