COX4I1 Monoclonal Antibody
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COX4I1 Monoclonal Antibody
| SKU # | E-AB-22002 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Applications | WB, IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Protein |
| Abbre | COX IV |
| Synonyms | AL024441, COX 4, COX IV, COX IV 1, COX IV-1, COX41, COX4B, COX4I1, COX4I2, COX4L2, COXIV, Cox4, Cox4a, Cytochrome C Oxidas, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform 1, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, mitochondrial |
| Swissprot | |
| Calculated MW | 20 kDa |
| Observed MW | 15 kDa |
| Cellular Localization | Mitochondrion inner membrane. |
| Tissue Specificity | Ubiquitous |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Metabolism, Signal Transduction, Tags and Cell Markers |
| Clone No. | 2D4 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-3000 |
| IHC | 1:50-300 |
| IF | 1:100-1:300 |
Background
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.