COPS3 Polyclonal Antibody Reactivity Human
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COPS3 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52946 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human COPS3 |
| Abbre | COPS3 |
| Synonyms | COP 9 (constitutive photomorphogenic) subunit 3, COP 9 complex S3, COP 9 complex homolog subunit 3, COP 9 complex subunit 3, COP 9 constitutive photomorphogenic homolog subunit 3, COP 9 homolog, COP 9 signalosome , Constitutive photomorphogenic homolog subunit 3 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 0.84 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for this gene.