CLEC1B Polyclonal Antibody Reactivity Human
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CLEC1B Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52143 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CLEC1B |
| Abbre | CLEC1B |
| Synonyms | member B, 1810061I13Rik, C type lectin domain family 1 member B, C type lectin like receptor 2, C-type lectin domain family 1, C-type lectin domain family 1 member B, C-type lectin-like receptor 2, C-type lectin-like receptor-2, CLC1B_HUMAN, CLEC 2, CLEC 2B, CLEC-2 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).