Claudin 4 Polyclonal Antibody Host Rabbit
SKU: E-AB-30945-200
Claudin 4 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-30945 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Claudin-4 |
| Abbre | Claudin 4 |
| Synonyms | CLD4, CLDN 4, CLDN4, CPE R, CPE receptor, CPE-R, CPE-receptor, CPER, CPETR, CPETR 1, CPETR1, Claudin-4, Claudin4, Clostridium perfringens enterotoxin receptor, Clostridium perfringens enterotoxin receptor 1, WBSCR8, Williams Beuren syndrome chromosome region 8 pro, hCPE R |
| Swissprot | |
| Calculated MW | 22 kDa |
| Observed MW | 22 kDa
|
| Cellular Localization | Cell junction>tight junction. Cell membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
| IF | 1:200-1:1000 |
Background
Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins. This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.