CD8A Polyclonal Antibody
SKU: E-AB-19675-200
CD8A Polyclonal Antibody
| SKU # | E-AB-19675 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CD8A |
| Abbre | CD8A |
| Synonyms | CD8, CD8 antigen alpha polypeptide, CD8 antigen alpha polypeptide (p32), CD8A, CD8A antigen, CD8A molecule, CD8a, LYT3, Leu2, Leu2 T lymphocyte antigen, Ly3, MAL, OKT8 T cell antigen, OTT, OTTHUMP00000160760, OTTHUMP00000160764, OTTHUMP00000203528, alpha polypeptide (p32) |
| Swissprot | |
| Cellular Localization | Cell membrane, Membrane, Secreted. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Immunology, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.