CD1D Polyclonal Antibody
SKU: E-AB-52320-200
CD1D Polyclonal Antibody
| SKU # | E-AB-52320 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CD1D |
| Abbre | CD1D |
| Synonyms | Antigen-presenting glycoprotein CD1d, CD1.1, CD1A, CD1D, CD1D antigen, CD1D antigen d polypeptide, CD1d, CD1d molecule, Cd1d1, HMC class I antigen like glycoprotein CD1D, Ly 38, MGC34622, R3, R3G1, T cell surface glycoprotein CD1d, Th, differentiation antigen CD1 alpha 3 |
| Swissprot | |
| Calculated MW | 38 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cell membrane. Endosome membrane. Lysosome membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Immunology, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack ,upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
CD1d is a member of the CD1 family of transmembrane glycoproteins,which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. CD1d is an antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on NKT cells. When activated,NKT cells rapidly produce Th1 and Th2 cytokines. The molecular weight of unglycosylated CD1d is 38 kDa,while glycosylated form of CD1d is 48-55 kDa.