CD16 Monoclonal Antibody
SKU: E-AB-22048-200
CD16 Monoclonal Antibody
| SKU # | E-AB-22048 |
| Reactivity | Human |
| Host | Mouse |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human |
| Applications | WB, IHC-p |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | CD16 |
| Synonyms | CD 16, CD 16a, CD16, CD16B, CD16a, Fc fragment of IgG, Fc fragment of IgG low affinity IIIa receptor (CD16), Fc gamma R3, Fc gamma receptor III 2 (CD 16), Fc gamma receptor III A, Fc of IgG, Fc-gamma R, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma receptor III2 (CD 16) |
| Swissprot | |
| Calculated MW | 28 kDa |
| Observed MW | 45 kDa |
| Cellular Localization | Extracellular region or secreted, extracellular exosome, extracellular region, Plasma Membrane, Other locations: anchored component of membrane, secretory granule membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Immunology, Stem Cells |
| Clone No. | 2B1 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-300 |
Background
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses.This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1.The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.