CD123 Monoclonal Antibody Synonyms CD123
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CD123 Monoclonal Antibody Synonyms CD123
Product Details
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | CD123 |
| Cellular Localization | Cytoplasm/cell membrane |
| Tissue Specificity | Tonsil |
| Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
| Shipping | Ice bag |
Background
CD123 is an alpha chain of the interleukin-3 receptor, which belongs to the type I cytokine receptor family. CD123 forms a heterodimer with CD131, the interleukin-3β receptor, to form the interleukin-3 receptor, with an alpha subunit that dominates cytokine specificity and a beta subunit that dominates signaling. CD123 is expressed on monocytes, neutrophils, basophils, eosinophils, megakaryocytes, red blood cell precursors, mast cells, macrophages and some B cell subsets. It is often used in combination with CD68, CD43 and CD4 for the diagnosis of blastic plasmacytoid dendritic cell neoplasm (BPDC).