CBS Polyclonal Antibody Store at -20°C
SKU: E-AB-14671-200
CBS Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14671 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CBS |
| Abbre | CBS |
| Synonyms | AI047524, AI303044, Beta thionase, Beta-thionase, CBS, Cbs, Cbs cystathionine beta-synthase, Cystathionine beta synthase, Cystathionine beta-synthase, EC 4.2.1.22, HIP 4, HIP4, MGC18856, MGC18895, MGC37300, Methylcysteine synthase, OTTHUMP00000109416, OTTHUMP00000109418, S |
| Swissprot | |
| Calculated MW | 61 kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
Background
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.