CALB1 Polyclonal Antibody Store at -20°C
SKU: E-AB-14812-200
CALB1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14812 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CALB1 |
| Abbre | CALB1 |
| Synonyms | CAB27, CALB, CALB 1, CALB1, Calbindin, Calbindin 1 28kDa, Calbindin D28, D 28K, D-28K, D28K, OTTHUMP00000166027, OTTHUMP00000225441, RTVL H protein, Vit, Vitamin D dependent calcium binding protein, Vitamin D dependent calcium binding protein avian type, avian-type |
| Swissprot | |
| Calculated MW | 30 kDa |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, Nucleus, Other locations: axon, dendrite, dendritic spine, neuronal cell body, synapse, terminal bouton. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted.