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BAK1 Polyclonal Antibody Store at -20°C
SKU: E-AB-13862-200
BAK1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13862 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human BAK1 |
| Abbre | BAK1 |
| Synonyms | Apoptosis regulator BAK, BAK, BAK like, BCL2 antagonist/killer 1, BCL2L7, Bak NT, Bak1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, Bcl2 like 7 Protein, Bcl2-L-7, CDN1, Cell death inhibitor 1, M |
| Swissprot | |
| Calculated MW | 23 kDa |
| Cellular Localization | Mitochondrion membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.