BAG3 Polyclonal Antibody Host Rabbit
SKU: E-AB-40660-100
BAG3 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40660 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human BAG3 protein expressed by E.coli |
| Abbre | BAG3 |
| Synonyms | BIS, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, BAG family molecular chaperone regulator 3 , BAG-3 |
| Swissprot | |
| Calculated MW | 62 kDa |
| Observed MW | 80 kDa |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Cell Biology, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:1000 |
Background
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.