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ARFGAP1 Polyclonal Antibody Store at -20°C
SKU: E-AB-10825-200
ARFGAP1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10825 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ARFGAP1 |
| Abbre | ARFGAP1 |
| Synonyms | ADP ribosylation factor 1 GTPase activating protein, ADP ribosylation factor GTPase activating protein 1, ADP-ribosylation factor 1 GTPase-activating protein, ADP-ribosylation factor GTPase-activating protein 1, ARF GAP 1, ARF1 directed GTPase activating prote |
| Swissprot | |
| Calculated MW | 45 kDa |
| Cellular Localization | Cytoplasm. Golgi apparatus. Associates with the Golgi complex. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
Background
The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1).The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles.Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments.The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine.Two transcript variants encoding different isoforms have been found for this gene.