ALDH4A1 Polyclonal Antibody Store at -20°C
SKU: E-AB-14536-200
ALDH4A1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14536 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ALDH4A1 |
| Abbre | ALDH4A1 |
| Synonyms | AL4A1, ALDH4, Aldehyde dehydrogenase, Aldehyde dehydrogenase family 4 member A1, Delta 1 pyrroline 5 carboxylate dehydrogenase, Delta-1-pyrro, aldehyde dehydrogenase 4, aldehyde dehydrogenase 4 family, aldh4a1, family 4, member 1, member A1, mitochondrial, subfamily A |
| Swissprot | |
| Calculated MW | 62 kDa |
| Cellular Localization | Mitochondrion matrix. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.