AIMP2 Polyclonal Antibody Host Rabbit
SKU: E-AB-40046-200
AIMP2 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40046 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein |
| Abbre | AIMP2 |
| Synonyms | AIMP2, ARS interacting multi functional protein 2, Aimp2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Aminoacyl tRNA synthetase complex interacting multifunctional protein 2, JTV 1, JTV 1 protein, JTV1, JTV1 gene, Multisynthase complex a |
| Swissprot | |
| Calculated MW | 35 kDa |
| Observed MW | 35 kDa |
| Cellular Localization | Cytoplasm>cytosol. Nucleus. Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Cell Biology, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:1000 |
Background
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.