AIM2 Polyclonal Antibody Store at -20°C
SKU: E-AB-10974-200
AIM2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10974 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human AIM2 |
| Abbre | AIM2 |
| Synonyms | AIM 2, AIM2, Absent in melanoma 2, Aim2, Interferon-inducible protein AIM2, OTTHUMP00000035296, PYHIN4 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family.Induced by IFN- , AIM2 is thought to act as a tumor suppressor by repressing NF B transcriptional activity.Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain.The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains.The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.