ABCB5 Monoclonal Antibody
SKU: E-AB-22032-200
ABCB5 Monoclonal Antibody
| SKU # | E-AB-22032 |
| Reactivity | Human |
| Host | Mouse |
| Applications | WB, IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human |
| Applications | WB, IHC-p, IF |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Abbre | ABCB5 |
| Synonyms | ABCB 5, ABCB5, ABCB5 P-gp, ABCB5alpha, ABCB5beta, ATP binding cassette protein, ATP binding cassette sub family B (MDR/TAP) member 5, ATP binding cassette sub family B member 5, ATP-binding cassette sub-family B member 5, EST422562, P glycoprotein ABCB5, P-gly |
| Swissprot | |
| Calculated MW | 90 kDa |
| Observed MW | 90 kDa |
| Cellular Localization | Cell membrane. |
| Tissue Specificity | Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Also expressed in several malignant tissues. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Clone No. | 7L3 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:3000 |
| IHC | 1:50-1:300 |
| IF | 1:100-1:300 |
Background
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules.