AARS2 Polyclonal Antibody Store at -20°C
SKU: E-AB-10116-200
AARS2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10116 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human AARS2 |
| Abbre | AARS2 |
| Synonyms | AARS 2, AARS2, AARSL, AlaRS, Alanine tRNA ligase, Alanine tRNA ligase 2 mitochondrial, Alanyl tRNA synthetase 2 mitochondrial, Alanyl tRNA synthetase like, COXPD8, Gm89, KIAA1270, LKENP, MGC69820, MT ALARS, MTALARS, Probable alanyl tRNA synthetase mitochondri, bA444E17.1 |
| Swissprot | |
| Calculated MW | 107 kDa |
| Cellular Localization | Mitochondrion matrix. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain