AANAT Polyclonal Antibody Store at -20°C
SKU: E-AB-14757-200
AANAT Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14757 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human AANAT |
| Abbre | AANAT |
| Synonyms | AA-NAT, Aanat, Aralkylamine N-acetyltransferase, Arylalkylamine N acetyltransferase, SNAT, Serotonin N-acetyltransferase, Serotonin acetylase |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene belongs to the acetyltransferase superfamily.It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland.Melatonin is essential for the function of the circadian clock that influences activity and sleep.This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation.This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.