ZFYVE27 Polyclonal Antibody Reactivity Human
SKU: E-AB-52901-200
ZFYVE27 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52901 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ZFYVE27 |
| Abbre | ZFYVE27 |
| Synonyms | Protrudin, RP11 459F3.2, SPG33 , ZFY27, ZFYVE27, Zinc finger FYVE domain containing protein 27 , Zinc finger FYVE domain-containing protein 27, zinc finger FYVE domain containing 27 |
| Swissprot | |
| Calculated MW | 46 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Recycling endosome membrane. Endoplasmic reticulum membrane. Cell projection>growth cone membrane. Cell membrane. Localizes at both dendrites and axons. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:300 |
Background
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.