VRK3 Polyclonal Antibody
SKU: E-AB-52423-200
VRK3 Polyclonal Antibody
| SKU # | E-AB-52423 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human VRK3 |
| Abbre | VRK3 |
| Synonyms | Inactive serine/threonine-protein kinase VRK3, Serine/threonine-protein pseudokinase VRK3, VRK3, Vaccinia-related kinase 3 |
| Swissprot | |
| Cellular Localization | Nucleus, nucleolus, Other locations: cytoplasm, intracellular membrane-bounded organelle. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis.In vitro assays indicate the protein lacks phosphorylation activity.The protein, however, likely retains its substrate binding capability.This gene is widely expressed in human tissues and its protein localizes to the nucleus.Alternative splicing results in multiple transcripts encoding different isoforms.