Product Details
Formal Name: (R)-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone · mesylate
Molecular Formula: C27H26N2O3 · CH3SO3H
Formula Weight: 522.62
CAS Number: 131543-23-2
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Cannabinoid CB1/CB2 agonist
Functions
High affinity cannabinoid receptor agonist (Ki = 62.3 nM for recombinant human CB1 and 3.3 nM for recombinant human CB2) with analgesic and anti-inflammatory activities. Activates p42 and p44 MAP kinase via cannabinoid receptor-mediated receptor signaling.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.