Tribioscience Tozasertib, Aurora Kinase Inhibitor (TBI2178)
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Tribioscience Tozasertib, Aurora Kinase Inhibitor (TBI2178)
Research Use Only. Not intended for human use.
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Product Details
Alternate Names: VX-680; MK-0457
Molecular Formula: C23H28N8OS
Formula Weight: 464.59
CAS Number: 639089-54-6
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 100 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Aurora kinase inhibitor
Functions
Inhibitor of Aurora kinases. Blocks cell cycle progressing, inhibits proliferation, and induces apoptosis in a wide range of cancer cell lines (IC50 = <10 μM for clear cell renal carcinoma).
Application Procedures
First dissolved in DMSO (up to 100 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.