Tribioscience NDGA, Antioxidant (TBI2678)

Tribioscience NDGA, Antioxidant (TBI2678)

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Product Details

Formal Name: 4,4′-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]

Alternate Names: Nordihydroguaiaretic acid

Molecular Formula: C₁₈H₂₂O₄

Formula Weight: 302.4

CAS Number: 500-38-9

Purity: >97%

Formulation: Powder

Solubility: dissolved in ethanol (50 mg/ml)

Storage: -20°C

Stability: ≥ 4 years.

Applications

Antioxidant

Functions

Inhibits lipoxygenases (IC₅₀=0.2, 30 and 30 µM for 5-, 12- and 15-LO respectively) selectively over cyclooxygenase (IC₅₀=100 µM). Inhibits rat epidermal and hepatic microsomal cytochrome P-450 (ID₅₀=40 µM).

Application Procedures

First dissolved in ethanol (50 mg/ml), then diluted to aqueous buffer. Solutions in ethanol may be stored at -20°C for up to 1 week.