Product Details
Formal Name: (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Alternate Names: N-(2-Hydroxyethyl)-1-deoxynojirimycin; BAY-1099
Molecular Formula: C8H17NO5
Formula Weight: 207.23
CAS Number: 72432-03-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml with warming), or in Water (up to 60 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
α-glucosidase inhibitor / antidiabetic
Functions
An α-glucosidase inhibitor which induces an enhanced and prolonged release of glucagon-like peptide-1, regulating appetite and stabilizing body weight in humans. Displays anti-atherothrombotic effect by reducing platelet activation and raising circulating adiponectin levels in patients with type 2 diabetes. Clinically useful antidiabetic agent.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml with warming), or in Water (up to 60 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.