First dissolved in DMSO (40 mg/ml); or ethanol (4 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Tribioscience Metergoline, Serotonin 5HT1,2,7 Antagonist (TBI3058)
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Tribioscience Metergoline, Serotonin 5HT1,2,7 Antagonist (TBI3058)
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Product Details
Formal Name: [(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester
Molecular Formula: C25H29N3O2
Formula Weight: 403.50
CAS Number: 17692-51-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (40 mg/ml); or ethanol (4 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Serotonin 5HT1,2,7 antagonist
Functions
Metergoline is an ergot alkaloid derivative acting as antagonist at serotonin 5HT1 and 5HT2 receptors and 5HT7 receptors. A safe and effective agent for management of hyperprolactinemic amenorrhea and anovulation. Displays a long lasting antidepressant effect in seasonal affective disorder.
Application Procedures