First dissolved in DMSO (up to 40 mg/ml) or in Water (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in
DMSO or distilled water may be stored at -20°C for up to 3 months.
Tribioscience Fluvastatin Na, HmgCoA Reductase Inhibitor (TBI2554)
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Tribioscience Fluvastatin Na, HmgCoA Reductase Inhibitor (TBI2554)
Research Use Only. Not intended for human use.
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Product Details
Formal Name: (+/-)(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt
Molecular Formula: C24H25FNO4 Na
Formula Weight: 466.45
CAS Number: 93957-55-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 40 mg/ml) or in Water (up to 10 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
HmgCoA reductase inhibitor
Functions
Potent inhibitor of HMG-CoA reductase, IC50=40-100 nM. Clinically useful, orally active antihypercholesterolemic agent. Inhibits vascular smooth muscle proliferation, IC50=70 nM. Displays antineuroinflammatory activity. Prevents lung adenocarcinoma bone metastasis by triggering autophagy. Attenuates cell proliferation in hepatocellular carcinoma.
Application Procedures