Tribioscience DBeQ, p97 AAA ATPase Inhibitor (TBI1196)

Tribioscience DBeQ, p97 AAA ATPase Inhibitor (TBI1196)

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Product Details

Formal Name: N,N’-Dibenzylquinazoline-2,4-diamine

Molecular Formula: C₂₂H₂₀N₄

Formula Weight: 340.43

CAS Number: 177355-84-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

p97 AAA ATPase inhibitor

Functions

A potent, selective and reversible inhibitor of the AAA-ATPase p97 (ATPase associated with diverse cellular activities). Ki=3.2 µM. It blocks ubiquitin-dependent protein clearance pathways. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.