Product Details
Formal Name: N-(5-Aminopentyl)-5-dimethylaminonaphthalene-1-sulfonamide
Alternate Names: Monodansyl cadaverine; MDC
Molecular Formula: C17H25N3O2S
Formula Weight: 335.46
CAS Number: 10121-91-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml with warming) or in Methanol (up to 10 mg/ml)
Storage: -20°C / protect from light
Stability: ≥ 1 year.
Applications
Autophagic vacuole dye
Functions
Preferentially accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids making it a very useful probe for monitoring autophagy. Inhibits EGF internalization. Competes with certain trans-aminases and can be used with antibody/affinity procedures to isolate resulting conjugates. Abs: 335 nm, Em: 510 nm
Application Procedures
First dissolved in DMSO (up to 10 mg/ml with warming) or in Methanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Methanol may be stored at -20°C for up to 1 month.