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Description: CD4 antigen is a 55 kDa, cell surface, type I membrane glycoprotein that belongs to the immunoglobulin superfamily. CD4 plays a crucial role in T cell development and is essential for the optimal function of mature T cells. It is expressed in most thymocytes, the majority of helper T cells, a subset of NK-T cells, dendritic cells, neutrophils, and macrophages. CD4 also acts as a receptor for the HIV-1 envelope glycoprotein gp120, facilitating viral entry into the host cell.
Applications:
- In vivo CD4+ T cell depletion
- Flow cytometry
- Western blot
Molecular Weight: 150 kDa
Immunogen: Mouse CTL clone V4
Host: Rat
Isotype: Rat IgG2b, kappa
Concentration: 4 mg/ml
Purity: >95%
Formulation: PBS, pH 6.5, no stabilizers or preservatives.
Endotoxin: < 2EU/mg
Clonality: Monoclonal
Sterility: 0.2 µm filtered
Storage: Store at 4°C for one month. Store at -20°C for long-term storage.