Tribioscience Anti-Mouse CD19 Rat Monoclonal Antibody (TBS10208)

Description: CD19 is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily, expressed on various stages of B cell development including early pro-B cells, late pro-B cells, memory B cells, plasmablasts, and some plasma cells. Aberrant CD19 signaling is linked to B cell malignancies, autoimmunity, and immunodeficiency. CD19 is also a target for chimeric antigen receptor (CAR) T cell therapies used in treating B cell malignancies.

Applications:

• In vivo B cell depletion
• In vivo CD19 neutralization
• In vitro B cell negative selection
• Flow cytometry

Molecular Weight: 150 kDa

Host: Rat

Isotype: Rat IgG2a Kappa

Concentration: 4 mg/ml

Purity: >95%

Formulation: PBS, pH 7.0, no stabilizers or preservatives.

Endotoxin: < 2EU/mg

Clonality: Monoclonal

Sterility: 0.2 µm filtered

Storage: Store at 4°C for one month. Store at -20°C for long-term storage.