Tribioscience Anisomycin, Protein Synthesis Inhibitor; Anoikis Sensitizer (TBI2056)
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Tribioscience Anisomycin, Protein Synthesis Inhibitor; Anoikis Sensitizer (TBI2056)
Research Use Only. Not intended for human use.
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Product Details
Formal Name: (2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate
Molecular Formula: C14H19NO4
Formula Weight: 265.30
CAS Number: 22862-76-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Protein synthesis inhibitor; Anoikis sensitizer
Functions
Activates JNK/SAPKs and induces c-fos and c-jun. Induces apoptosis and sensitizes cells to anoikis. Displays immunosuppressive activity, inhibiting T cell proliferation in mouse models. Inhibits consolidation of new context-specific long-term memories. Protein synthesis inhibitor (inhibits translation). Cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.